The largest industry sectors by employment in Indianapolis are manufacturing, health care and social services, and retail trade. Compared to Indiana as a whole, the Indianapolis metropolitan area has a lower proportion of manufacturing jobs and a higher concentration of jobs in wholesale trade; administrative, support, and waste management; professional, scientific, and technical services; and transportation and warehousing. Many of Indiana’s largest and most recognized companies are headquartered in Indianapolis, including pharmaceutical manufacturer Eli Lilly and Company; wireless distribution and logistics provider Brightpoint; health insurance provider Wellpoint; retailers Marsh Supermarkets, Finish Line, Republic Airways Holdings and REIT Simon Property Group. The U.S. headquarters of Roche Diagnostics, Conseco, First Internet Bank of Indiana, Dow AgroSciences, Emmis Communications, Steak ‘n Shake, and Allison Transmission are also located in Indianapolis. Other major Indianapolis area employers include Indiana University Health, Sallie Mae, Cook Group, Rolls-Royce, Delta Faucet Company, Ice Miller, Raytheon, Carrier and General Motors.