Philadelphia is the center of economic activity in Pennsylvania. According to the Bureau of Economic Analysis, the Philadelphia area is the seventh-largest metropolitan economy in the United States. Philadelphia ranks ninth among world cities and fourth in the nation. The city is also the nation’s fourth-largest consumer media market. The city is home to the Philadelphia Stock Exchange and several Fortune 500 companies. Philadelphia’s economic sectors include information technology, manufacturing, oil refining, food processing, health care and biotechnology, tourism and financial services. Philadelphia has shifted to an information technology and service-based economy. Financial activities account for the largest sector of the metro economy, and it is one of the largest health education and research centers in the United States.